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or Brit  ca*na*li*sa*tion  n 1  :  surgical formation of holes or canals for drainage without tubes  2  :  natural formation of new channels in tissue (as formation of new blood vessels through a blood clot)  3  :  establishment of new pathways in the central nervous system by repeated passage of nerve impulses  4  :  the developmental buffering and homeostatic processes by which a particular kind of organism forms a relatively constant phenotype although individuals may have a variety of genotypes and environmental conditions may vary .

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