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n 1  :  a relatively permanent change in hereditary material involving either a physical change in chromosome relations or a biochemical change in the codons that make up genes : also  :  the process of producing a mutation  2  :  an individual, strain, or trait resulting from mutation mu*ta*tion*al adj mu*ta*tion*al*ly adv 
Similar sounding terms:  me·di·a·tion 

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