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chronic myelogenous leukemia

n :  myelogenous leukemia that is marked by an abnormal increase in mature and immature granulocytes (as neutrophils, eosinophils, and myelocytes) esp. in bone marrow and blood, that is characterized by fatigue, weakness, loss of appetite, spleen and liver enlargement, anemia, thrombocytopenia, and ultimately a dangerous increase in blast cells and esp. myeloblasts and lymphoblasts, that occurs esp. in adults, and that is associated with the presence of the Philadelphia chromosome - abbr. CML - called also chronic myelocytic leukemia , chronic myeloid leukemia , chronic granulocytic leukemia  - compare ACUTE MYELOGENOUS LEUKEMIA  .

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