also placque n 1 a : a localized abnormal patch on a body part or surface and esp. on the skin <psoriatic > b : a film of mucus that harbors bacteria on a tooth c : an atherosclerotic lesion d : a histopathologic lesion of brain tissue that is characteristic of Alzheimer's disease and consists of a cluster of degenerating nerve endings and dendrites around a core of amyloid - called also senile plaque 2 : a visibly distinct and esp. a clear or opaque area in a bacterial culture produced by damage to or destruction of cells by a virus .
Similar sounding terms: HPLC plague pli·ca plug
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